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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-21-5p
ncRNA name hsa-miR-21-5p
ncRNA Category miRNA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line serum; human RPE cell line ARPE-19
Methods qPCR, qRT-PCR, apoptosis assay, angiogenesis assay
Expression pattern detectable
Functional description Human Apoptosis miScript miRNA PCR Array profiling was done using ARPE-19 cells treated with AMD derived exosomes. The Human Apoptosis miScript miRNA PCR Array profiles the expression of 84 miRNAs that regulate programmed cell death.
PubMed ID 27826921
Year 2017
Title Exosomal MicroRNA Discovery in Age-Related Macular Degeneration
Drug-related ncRNA NO

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